My niece, Grace - my wife's sister's daughter - informed us she was gay in her early 20s a few years ago. Cool, fine, we love you, Grace (and her hot Indian partner!). Now a few years later, she tells us she feels more like she wants to be gender-neutral, and now prefers us to use the third-person pronoun "them, they, etc." They've changed their name to the more neutral "Grayson." All this is fine with my wife and I, and we're full of support for Grayson. Anyway, our confusion comes in what to call Grayson in terms of familial relation. "Niece" is no longer appropriate. Their parents can get away with "offspring" or "Child." No idea what their brother will refer to them as. "My sister-in-law's gender-fluid offspring" is a bit of a mouthful. @Nova ? Anyone?