Next stop: HIV?!

NAHTMMM · Apr 6, 2021

Novel HIV vaccine approach shows promise in “landmark” first-in-human trial

A novel vaccine approach for the prevention of HIV has shown promise in Phase I trials, reported IAVI and Scripps Research. According to the organisations, the vaccine successfully stimulated the production of the rare immune cells needed to generate antibodies against HIV in 97 percent of participants.

The vaccine is being developed to act as an immune primer, to trigger the activation of naïve B cells via a process called germline-targeting, as the first stage in a multi-step vaccine regimen to elicit the production of many different types of broadly neutralizing antibodies (bnAbs). Stimulating the production of bnAbs has been pursued as a holy grail in HIV for decades. It is hoped that these specialised blood proteins could attach to HIV surface proteins called spikes, which allow the virus to enter human cells, and disable them via a difficult-to-access regions that does not vary much from strain to strain.

[...]

As a next step, the collaborators are partnering with the biotechnology company Moderna to develop and test an mRNA-based vaccine that harnesses the approach to produce the same beneficial immune cells. According to the team, using mRNA technology could significantly accelerate the pace of HIV vaccine development, as it did with vaccines for COVID-19.
Click to expand...

We Are Borg · Apr 6, 2021

Where do the 5G Bill Gates microchip trackers fit in to this new vaccine?

Bailey · Apr 7, 2021

If this pans out and provides lasting immunity it will be amazing.

Log in or Sign up

Next stop: HIV?!

NAHTMMM Perpetually sondering

We Are Borg Republican Democrat

Bailey It's always Christmas Eve Super Moderator

Log in or Sign up

Next stop: HIV?!

NAHTMMM Perpetually sondering

We Are Borg Republican Democrat

Bailey It's always Christmas Eve Super Moderator

Useful Searches