https://www.news-medical.net/news/2...early-20025-in-ventilated-COVID-patients.aspx Hydroxychloroquine + Azithromycin therapy at a higher dose improved survival by nearly 200% in ventilated COVID patients
Not peer reviewed. The lead name on the study is a gynecologist. Here are the others and the practice they're associated with. The study suggests ventilated patients might benefit; it does not suggest HQC and/or AZM be used as a prophylactic. Here's the full text. Here's another article from a year ago that suggests HQC and AZM may cause increased heart problems.
Not peer reviewed, probably will be not be published as-is. 1. Claims to be a RCT; it's not. 2. This is minor, but indicative: it treats all corticosteroids as convertible to dexamethasone-equivalent when previous literature indicated that dexamethasone was more effective than other steroids at treating COVID-19 at what would otherwise be equivalent doses (Summary here). 3. Probably the most-fatal flaw: major time-series survivorship bias -- patients can't get to the higher cumulative doses if they die first, thus only patients who survived got the highest cumulative doses. This is further magnified by arbitrarily dividing the "treatment" group from the "non-treatment" group by cumulative dose received. "The people who died later survived longer than those who died early" is not exactly news. Like, we know that the longer you're on a ventilator, the less likely you'll survive to get off it, but looking at the data the same way as this paper does, you'd see the same curve from figure 1: the longer people are on the ventilator, the longer they survive, because death is causing the discontinuation of the treatment, not recovery. The lack of cardiotoxicity (QTc prolongation) in the treatment group is probably the most interesting result in the paper (albeit one that's in conflict with the article steve linked to), and could be followed up on, but basing any treatment plan on it does kinda presume that hydroxychloroquine and azithromycin are actually useful together in treating anything at all.
But at least they’re doing something to get more people vaccinated. My state isn’t doing anything, it seems.
Research seems to indicate that in immuno-compromised individuals COVID-19 has a very high mutation rate. That's a link to the pre-print paper and it hasn't been peer-reviewed as of yet.
Mom's care facility is on lockdown for 2 weeks, since somebody in there tested positive. My sister can't even go in to see her, and they're both vaxed.
My friend in Kolkata said she just got her first dose with her niece yesterday Their second dose is in approximately 84 days
That's about 1000x more likely than "COVID19 was a bio-weapon released on purpose" like some people that run in my circles might claim.